Go to the doctor and they won’t begin to treat you without taking your history — and not just yours, but that of your parents and grandparents before you. Pulitzer Prize-winning journalist Isabel Wilkerson points this out as she reflects on her epic work of narrative nonfiction, The Warmth of Other Suns. She’s immersed herself in the stories of the Great Migration, the movement of six million African Americans to northern U.S. cities in the 20th century. The book is a carrier of histories and truths that help make sense of human and social challenges at the heart of our life together now.

This year Muslims are experiencing a Ramadan like no other. The month is usually a period of both intimacy and great community. Now Muslims are improvising, as in many places the rituals of Ramadan must be experienced at home or online. This show, recorded in 2009, grew out of an invitation to Muslim listeners to reflect on what it means to be part of what often is referred to in the abstract as “the Muslim world.” We received responses from all over the world and were struck by the vivid stories about Ramadan itself, across a remarkable spectrum of life and spiritual sensibility.

We’re in a season of renewal in the natural world and in spiritual traditions; both Easter and Passover this year are utterly transformed. It’s drawing us back to the wisdom of Br. David Steindl-Rast, who makes useful distinctions around experiences that are life-giving and resilience-making yet can feel absurd to speak of in a moment like this. A Benedictine monk for over 60 years, Steindl-Rast was formed by 20th-century catastrophes. He calls joy “the happiness that doesn’t depend on what happens.” And his gratefulness is not an easy gratitude or thanksgiving — but a full-blooded, reality-based practice and choice.

The wise and beloved Vatican astronomer Father George Coyne died last week. Like most of the Vatican astronomers across history, he was also a Jesuit. More than 30 objects on the moon are named after the Jesuits who mapped it and ten Jesuits in history have had asteroids named after them. Father Coyne was one of the few with this distinction, alongside his friend and fellow Vatican astronomer Brother Guy Consolmagno. In a conversation filled with laughter, we experience the spacious way the two of them approached life, faith, and the universe.

Civil rights legend Ruby Sales learned to ask “Where does it hurt?” because it’s a question that drives to the heart of the matter — and a question we scarcely know how to ask in public life now. Sales says we must be as clear about what we love as about what we hate if we want to make change. And even as she unsettles some of what we think we know about the force of religion in civil rights history, she names a “spiritual crisis of white America” as a calling of today.

Fr. Greg Boyle makes amazingly winsome connections between things like service and delight, compassion and awe. He landed as an idealistic young Jesuit in a gang-heavy neighborhood of Los Angeles three decades ago. Now he heads Homeboy Industries, which employs former gang members in a constellation of businesses from screen printing to a farmers’ market to a bakery. This is not work of helping, he says, but of finding kinship.

“Our discomfort and our grappling is not a sign of failure,” America Ferrera says, “it’s a sign that we’re living at the edge of our imaginations.” She is a culture-shifting actor and artist. John Paul Lederach is one of our greatest living architects of social transformation. From the inaugural On Being Gathering, a revelatory, joyous exploration of the ingredients of social courage and how change really happens in generational time.

She has called Brain Pickings, her invention and labor of love, a “human-powered discovery engine for interestingness.” What Maria Popova really delivers, to hundreds of thousands of people each day, is wisdom of the old-fashioned sort, presented in new ways. She cross-pollinates between philosophy and design, physics and poetry, the intellectual and the experiential. We explore her gleanings on what it means to lead a good life — intellectually, creatively, and spiritually.

Pico Iyer is one of our most eloquent explorers of what he calls the “inner world” — in himself and in the 21st century world at large. The journalist and novelist travels the globe from Ethiopia to North Korea and lives in Japan. But he also experiences a remote Benedictine hermitage as his second home, retreating there many times each year. In this intimate conversation, we explore the discoveries he’s making and his practice of “the art of stillness.”

“If there isn’t the crack in the middle where there’s some people on both sides who absolutely refuse to see the other as evil, this is going to continue.”

The focus of our national fight over abortion may change, but this hasn’t changed for decades: we collapse this most intimate and complex of human dilemmas to two sides. We’ve been looking yet again for wisdom away from the turbulent news cycle and keep returning to this conversation Krista had with Frances Kissling. She is a “bridge person” in the abortion debate: a long-time pro-choice activist who has sought to come into relationship with her political opposites. Now she’s controversial on both sides, but speaks from a place that many of us would like to map out between the poles. She has experienced something more powerful, as she tells it, than defining common ground — and this has lessons for other issues in our common life and our struggles with people with whom we disagree the most.

“We are flying too low. We built this universe, this technology, these connections, this society, and all we can do with it is make junk? All we can do with it is put on stupid entertainments? I’m not buying it.”

Seth Godin is wise and infectiously curious about life, the internet, and everything. He was one of the first people to name the “connection economy.”  And even as we’re seeing its dark side, he helps us hold on to the highest human potential the digital age still calls us to. His daily blog is indispensable reading for many of us. He’s a long-time mentor to Krista. This interview happened in 2012. Seth now has a new podcast, Akimbo, and a new book coming out, This Is Marketing: You Can’t Be Seen Until You Learn to See.

The great cellist Yo-Yo Ma is a citizen artist and a forensic musicologist, decoding the work of musical creators across time and space. In his art, Yo-Yo Ma resists fixed boundaries, and would like to rename classical music just “music” — born in improvisation, and traversing territory as vast and fluid as the world we inhabit. In this generous and intimate conversation, he shares his philosophy of curiosity about life, and of performance as hospitality.

Nothing is helping us more right now, as we watch human tragedies unfold on the U.S.-Mexican border and elsewhere, than a conversation Krista had last year with literary historian Lyndsey Stonebridge — on thinking and friendship in dark times. She applies the moral clarity of the 20th-century philosopher Hannah Arendt to now — an invitation to dwell on the human essence of events we analyze as political and economic. Our dramas of exile and displacement are existential, she says — about who we will all be as people and political community. What Arendt called the “banality of evil” was at root an inability to hear another voice.

Oceanographer Sylvia Earle was the first person to walk solo on the bottom of the sea, under a quarter mile of water. She has watched humanity’s enduring fascination with “outer space” while she has delighted in “inner space” — the alien and increasingly endangered worlds beneath earth’s waters. These frontiers, as Sylvia Earle points out, are our very life-support system. She takes us inside the knowledge she’s gathered from a lifetime of research and literally swimming with sharks.

It’s easy to despair at all the bad news and horrific pictures that come at us daily. But Roshi Joan Halifax says this is a form of empathy that works against us. There’s such a thing as pathological altruism. This zen abbot and medical anthropologist has nourishing wisdom as we face suffering in the world.

“In a free society, some are guilty, but all are responsible.” A mystic, a 20th-century religious intellectual, a social change agent, Rabbi Abraham Joshua Heschel marched alongside Martin Luther King, Jr., famously saying afterwards that he felt his legs were praying. Heschel’s poetic theological writings are still read and widely studied today. His faith was as much about “radical amazement” as it was about certainty. And he embodied the passionate social engagement of the prophets, drawing on wisdom at once provocative and nourishing.