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Anthropologist Helen Fisher explores the biological workings of our intimate passions, the brew of chemicals, hormones, and neurotransmitters that make the thrilling and sometimes treacherous realms of love and sex. In the research she does for match.com and her TED Talks that have been viewed by millions of people, she wields science as an entertaining, if sobering, lens on what feel like the most meaningful encounters of our lives. In this deeply personal conversation, she shows how it is possible to take on this knowledge as a form of wisdom and power.

A literary thinker with a “telescopic view of time”; an astrophysicist with an eye to “cultural evolution towards good.” What unfolds between these two is joyous, dynamic, and unexpectedly vulnerable — rich with cosmic imagining, civic pondering, and even some fresh definitions of the soul. A live taping from the inaugural On Being Gathering at the 1440 Multiversity in California.

Stephen Batchelor’s secular Buddhism speaks to the mystery and vitality of spiritual life in every form. For him, secularism opens to doubt and questioning as a radical basis for spiritual life. Above all, he understands Buddhism without transcendent beliefs like karma or reincarnation to become something urgent to do, not to believe in.

Oceanographer Sylvia Earle was the first person to walk solo on the bottom of the sea, under a quarter mile of water. She has watched humanity’s enduring fascination with “outer space” while she has delighted in “inner space” — the alien and increasingly endangered worlds beneath earth’s waters. These frontiers, as Sylvia Earle points out, are our very life-support system. She takes us inside the knowledge she’s gathered from a lifetime of research and literally swimming with sharks.

Movies delight and inspire and repel. They’re places the big questions we take up at On Being land in the heart of our lives. They change our lives and our life together. Get out the popcorn for this show, and immerse yourself in film scores and iconic movie moments — with David Greene on how Star Wars changed him, Ashley C. Ford on The Nightmare Before Christmas, Rubén Blades on the 1943 noir Western The Ox-Bow Incident, and more.

The tensions of our time are well-known. But there are stories that are not being told, because they are not violent and not shouting to be heard. One of them is that all over this country, synagogues and mosques, Muslims and Jews, have been coming to know one another. There is friendship. There are initiatives that are patiently, and at human scale, planting the seeds for new realities across generational time. As part of the Civil Conversations Project, a live conversation at the Union for Reform Judaism’s General Assembly in Boston between Imam Abdullah Antepli and Rabbi Sarah Bassin.

“A dysfunctional family is any family with more than one person in it.” Mary Karr has a captivating ability to give voice to what is funny in life’s most heartbreaking moments. She is beloved for her salty memoirs in which she traces her harrowing childhood in southeast Texas — with a mother who once tried to kill her with a butcher’s knife and her own adult struggles with alcoholism and breakdown. Mary Karr embodies this wryness and wildness in her lesser-known spiritual practice as a devout Catholic — an unexpected move she made in mid-life.

“It’s very likely that the universe is really a kind of a question, rather than the answer to anything,” says philosopher technologist Kevin Kelly. He was the founding editor of WIRED and is an original thinker on shaping the character and spiritual meaning of technology. He says our role as good askers of questions will remain the most important contribution of our species in a coming world of AI.

The poet Christian Wiman is giving voice to the hunger and challenge of being religious now. He had a charismatic Texas Christian upbringing, and was later agnostic. He became actively religious again as he found love in his mid 30s, and was diagnosed with cancer. He’s written, “How does one remember God, reach for God, realize God in the midst of one’s life if one is constantly being overwhelmed by that life?”

We often find ourselves talking to poets and writers about the vivid connections between art and faith. This special hour came out of a live collaboration between On Being and Selected Shorts at Symphony Space in New York. Claire Danes, Ellen Burstyn, Julie White, and U.S. poet laureate Tracy K. Smith joined us with stories and poems about meaning and mystery.