Neuroscientist Richard Davidson is one of the central people who’s helped us begin to see inside our brains. His work has illuminated the rich interplay between things we saw as separate not that long ago: body, mind, spirit, emotion, behavior, and genetics. Richard is applying what he’s learning about imparting qualities of character — like kindness and practical love — in lives and in classrooms. This live conversation was recorded at the Orange County Department of Education in Costa Mesa, California.

“Let death be what takes us,” Dr. BJ Miller has written, “not a lack of imagination.” As a palliative care physician, he brings a design sensibility to the matter of living until we die. And he’s largely redesigned his sense of own physical presence after an accident at college left him without both of his legs and part of one arm. He offers a transformative reframing on our imperfect bodies, the ways we move through the world, and all that we don’t control.

A transformation of medicine is underway, a transition from a science of treating disease to a science of health. Mark Hyman is a family physician and a pioneer in the new discipline of functional medicine. James Gordon is an expert in using mind-body medicine to heal depression, anxiety, and psychological trauma. Penny George became a philanthropist of integrative medicine after she experienced cancer in mid-life. Before a live audience at the University of Minnesota, they discuss the challenge and promise of aligning medicine with a 21st century understanding of human wholeness.

From the moment of his diagnosis with ALS, Bruce Kramer began writing — openly, deeply, and spiritually — about his struggle, as he puts it, to live while dying. He died on March 23, 2015, while we were in production on this show. His words hold abiding joy and beauty, and reveal an unexpected view opened by this disease.

Eve Ensler has helped women all over the world tell the stories of their lives through the stories of their bodies. Her play, “The Vagina Monologues,” has become a global force in the face of violence against women and girls. But she herself also had a violent childhood. And it turns out that she, like so many Western women, was obsessed by her body and yet not inhabiting it without even knowing she wasn’t inhabiting her body — until she got cancer.

Yoga has infiltrated law schools and strip malls, churches and hospitals. This 5,000-year-old spiritual technology is converging with 21st-century medical science and with many religious and philosophical perspectives. Seane Corn takes us inside the practicalities and power of yoga. She describes how it helps her face the darkness in herself and the world, and how she’s come to see yoga as a form of body prayer.

Who knew that we learn empathy, trust, irony, and problem solving through play — something the dictionary defines as “pleasurable and apparently purposeless activity.” Dr. Stuart Brown suggests that the rough-and-tumble play of children actually prevents violent behavior, and that play can grow human talents and character across a lifetime. Play, as he studies it, is an indispensable part of being human.

Dr. Sherwin Nuland died this week at the age of 83. He became well-known for his first book, How We Die, which won the National Book Award. For him, pondering death was a way of wondering at life — and the infinite variety of processes that maintain human life moment to moment. He reflects on the meaning of life by way of scrupulous and elegant detail about human physiology.

The light and smells in places like hospitals can often depress us. And, our favorite room at home keeps us sane. But why? Immunologist Esther Sternberg explains the scientific research revealing how physical spaces create stress and make us sick — and how good design can trigger our “brain’s internal pharmacies” and help heal us.