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Neuroscientist Richard Davidson is one of the central people who’s helped us begin to see inside our brains. His work has illuminated the rich interplay between things we saw as separate not that long ago: body, mind, spirit, emotion, behavior, and genetics. Richard is applying what he’s learning about imparting qualities of character — like kindness and practical love — in lives and in classrooms. This live conversation was recorded at the Orange County Department of Education in Costa Mesa, California.

Mary Oliver was one of our greatest and most beloved poets. She is often quoted by people across ages and backgrounds — and it’s fitting, since she described poetry as a sacred community ritual. “When you write a poem, you write it for anybody and everybody,” she said. Mary died on January 17, 2019, at the age of 83. She was a prolific and decorated poet, whose honors included the Pulitzer Prize and the National Book Award. In this 2015 conversation — one of the rare interviews she granted during her lifetime — she discussed the wisdom of the world, the salvation of poetry, and the life behind her writing.

The family therapist who created the field of “ambiguous loss” — loss without closure. Complicated grief: parents, divorce, addiction, dementia, aging. “You love somebody. And when they’re lost, you still care about them. You can’t just turn it off.”

There is no such thing as closure. In fact, Pauline Boss says, the idea of closure leads us astray. It’s a myth we need to put aside, like the idea we’ve accepted that grief has five linear stages and we come out the other side done with it. She coined the term “ambiguous loss,” creating a new field in family therapy and psychology. She has wisdom for the complicated griefs and losses in all of our lives and for how we best approach the losses of others.

Pauline Boss is professor emeritus at the University of Minnesota. She is the author of “Loss, Trauma, and Resilience: Therapeutic Work with Ambiguous Loss,” “Loving Someone Who Has Dementia,” and “Ambiguous Loss.” She has also pioneered a global online course with the University of Minnesota called “Ambiguous Loss: Its Meaning and Application.”

Rachel Naomi Remen’s lifelong struggle with Crohn’s disease has shaped her practice of medicine, and she in turn is helping to reshape the art of healing. “The way we deal with loss shapes our capacity to be present to life more than anything else,” she says. And each of us, with our wounds and our flaws, has exactly what’s needed to help repair the part of the world that we can see and touch.

Anthropologist Helen Fisher explores the biological workings of our intimate passions, the brew of chemicals, hormones, and neurotransmitters that make the thrilling and sometimes treacherous realms of love and sex. In the research she does for match.com and her TED Talks that have been viewed by millions of people, she wields science as an entertaining, if sobering, lens on what feel like the most meaningful encounters of our lives. In this deeply personal conversation, she shows how it is possible to take on this knowledge as a form of wisdom and power.

New research reveals that trauma experienced in childhood has longterm damaging effects on quality of life and lifespan. But the same research shows that adults play a critical role in helping children overcome this damage.

The new field of epigenetics sees that genes can be turned on and off and expressed differently through changes in environment and behavior. Rachel Yehuda is a pioneer in understanding how the effects of stress and trauma can transmit biologically, beyond cataclysmic events, to the next generation. She has studied the children of Holocaust survivors and of pregnant women who survived the 9/11 attacks. But her science is a form of power for flourishing beyond the traumas large and small that mark each of our lives and those of our families and communities.

What does a good day look like? This is the question that transformed Atul Gawande’s practice of medicine. He’s a citizen physician on the frontiers of human agency and meaning in light of what modern medicine makes possible. In his writing in The New Yorker, and in his book Being Mortal, he’s opening a new conversation about what dying has to do with living.

We explore a topic our listeners have called out as a passionate force and a connector across all kinds of boundaries in American culture: running. Not just as exercise, or as a merely physical pursuit, but running as a source of bonding between parents and children and friends; running as an interplay between competition and contemplation; running and body image and survival and healing.

Black Lives Matter co-founder and artist Patrisse Cullors presents a luminous vision of the spiritual core of Black Lives Matter and a resilient world in the making. She joins Dr. Robert Ross, a physician and philanthropist on the cutting edge of learning how trauma can be healed in bodies and communities. A cross-generational reflection on evolving social change.

Sheryl Sandberg is synonymous with Facebook and Silicon Valley success, and she’s the voice of Lean In. She joins us, frank and vulnerable, together with the psychologist Adam Grant. His friendship — and his research on resilience — helped her survive the shocking death of her husband while on vacation. They share what they’ve learned about planting deep resilience in ourselves and our children, and even reclaiming joy. There is so much learning here on facing the unimaginable when it arrives in our lives and being more practically caring towards the losses woven into lives all around us.

Human memory is a sensory experience, says psychiatrist Bessel van der Kolk. Through his longtime research and innovation in trauma treatment, he shares what he’s learning about how bodywork like yoga or eye movement therapy can restore a sense of goodness and safety. What he’s learning speaks to a resilience we can all cultivate in the face of the overwhelming events — which, after all, make up the drama of culture, of news, and of life.

Kevin Kling is part funny guy, part poet and playwright, part wise man. A treasured figure on the national storytelling circuit, his voice inhabits an unusual space — where a homegrown Minnesota wit meets Dante and Shakespeare. Born with a disabled left arm, he lost the use of his right one after a motorcycle accident nearly killed him. He shares his special angle on life’s humor and its ruptures — and why we turn loss into story.

“Let death be what takes us,” Dr. BJ Miller has written, “not a lack of imagination.” As a palliative care physician, he brings a design sensibility to the matter of living until we die. And he’s largely redesigned his sense of own physical presence after an accident at college left him without both of his legs and part of one arm. He offers a transformative reframing on our imperfect bodies, the ways we move through the world, and all that we don’t control.

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